ROCKVILLE, Md., Oct. 24, 2014 /PRNewswire/ -- RegeneRx Biopharmaceuticals, Inc. (OTCBB: RGRX) ("the Company" or "RegeneRx") today reported on data presented at the Fourth International Symposium on Thymosins in Health and Disease in Rome, Italy.
"When thymosin beta 4 (TB4) linked with rhodamine (a fluorescent tracer dye) was injected into the peritoneal cavity in a rodent model of stroke, it was visualized outside of blood vessels and throughout the brain parenchyma (the functional tissue of the brain). The leakage of TB4 in this rat model of embolic stroke confirmed our hypothesis that TB4 crossed the blood brain barrier since previous experiments using MRI and gadolinium showed compromise of the blood brain barrier in this model of embolic stroke," reported Dr. Daniel Morris, Senior Staff Physician, Department of Emergency Medicine, Henry Ford Health System, Detroit, MI.
These experiments show the ability of TB4 to cross the blood-brain barrier, which is impermeable to most drugs. Thus, health care providers would potentially have a novel means to treat patients of neurological injury in which the blood brain barrier is compromised, such as stroke, by systemically administering TB4 to accelerate repair and regenerate damaged brain tissue.
About RegeneRx Biopharmaceuticals, Inc. (www.regenerx.com)
RegeneRx is focused on the development of a novel therapeutic peptide, Thymosin beta 4, for tissue and organ protection, repair and regeneration. RegeneRx currently has three drug candidates in clinical development for ophthalmic, cardiac, CNS and dermal indications, strategic licensing agreements in China, the EU, and in other Pan Asia countries, including Korea, Japan and Australia, and has an extensive worldwide patent portfolio covering its products.
Any statements in this press release that are not historical facts are forward-looking statements made under the provisions of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements concerning research and clinical development and future commercialization of the Company's drug candidates, the design and length of clinical trials, and other regulatory interaction. Any forward-looking statements involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. There can also be no assurance that any clinical trial undertaken by RegeneRx or its licensees will be commercially successful or that the FDA or other government agency will not have additional comments, restrictions, or guidance revisions regarding future clinical development or drug applications. Please view these and other risks described in the Company's filings with the Securities and Exchange Commission ("SEC"), including those identified in the "Risk Factors" section of the annual report on Form 10-K for the year ended December 31, 2013, and subsequent quarterly reports filed on Form 10-Q, as well as other filings it makes with the SEC. Any forward-looking statements in this press release represent the Company's views only as of the date of this release and should not be relied upon as representing its views as of any subsequent date. The Company specifically disclaims any obligation to update this information, as a result of future events or otherwise, except as required by applicable law.
SOURCE RegeneRx Biopharmaceuticals, Inc.